9/30/10
Wretchedness
9/29/10
ADHD
New study claims ADHD 'has a genetic link'By Jane DreaperHealth correspondent, BBC News
The first direct evidence of a genetic link to attention-deficit hyperactivity disorder has been found, a study says.
Scientists from Cardiff University, writing in The Lancet, said the disorder was a brain problem like autism - not due to bad parenting.
They analysed stretches of DNA from 366 children who had been diagnosed with the disorder.
But one clinical psychologist argued that what happened in children's early years was more crucial than genetics.
At least 2% of children in the UK are thought to have attention-deficit hyperactivity disorder (ADHD).
Affected children are restless and impulsive. They may also have destructive tendencies, and experience serious problems at school and within family life.
The researchers compared genetic samples from ADHD children, with DNA from 1,047 people without the condition.
They found that 15% of the ADHD group had large and rare variations in their DNA - compared with 7% in the control group.
Professor Anita Thapar said: "We found that, compared with the control group, the children with ADHD have a much higher rate of chunks of DNA that are either duplicated or missing.
"This is really exciting - because it gives us the first direct genetic link to ADHD.
"We have looked at lots of potential risk factors in the environment - such as parenting or what happens before birth - but there isn't the evidence to say they're linked to ADHD.
"There's a lot of public misunderstanding about ADHD. Some people say it's not a real disorder, or that it's the result of bad parenting.
"Finding this direct link should address the issue of stigma."
The researchers stressed that there is no single gene behind ADHD, and the work is at too early a stage to lead to any test for the disorder.
But they hope the study will help unravel the biological basis of ADHD. This could eventually lead to new treatments.
The work was largely funded by the Wellcome Trust, with extra support from the Medical Research Council.
The chief executive of a charity and support group ADDIS, Andrea Bilbow, said: "We are very excited. We've always known there was a genetic link - through studies and anecdotally.
"This paper will help us deal more confidently with the sceptics, who are always so eager to blame parents or teachers. It shows there is a definite genetic anomaly in children with ADHD."
But the study has been criticised by the clinical child psychologist and broadcaster, Oliver James.
He cited studies which looked at the effect of anxiety among pregnant women, and disturbed early relations between mothers and their babies.
He said: "Only 57 out of the 366 children with ADHD had the genetic variant supposed to be a cause of the illness.
"That would suggest that other factors are the main cause in the vast majority of cases.
"Genes hardly explain at all why some kids have ADHD and not others."
Do you have experience of attention-deficit hyperactivity disorder? Do you have a child with ADHD? Send your comments using the post form below:
9/28/10
Empowerment: Amra Shakti Shalli - We Are Powerful
9/19/10
Blues Music
Wasted Life
Vigil for woman killed after shoplifting assault
Last Updated: Sunday, September 19, 2010 | 11:25 AM CT
CBC News
9/16/10
The Playful Search For Beauty
She even has a playful way of giving her talk in front of a large audience.
Hard Times
9/12/10
Janis Joplin- Down and Out
Janis Joplin singing "Nobody Knows You When You're Down And Out" from album "This Is Janis Joplin"
Lyrics:
Well, once I lived the life of a millionaire, spending my money, no, I didn't care
Takin' my friend John out for a mighty good time
Buyin' high-priced liquor, champagne and wine
Then I began to fall so low, didn't have a friend, nor no place to go
If I get my hands on a dollar again
I'm goin' to hold on to it until the eagle grins
Soon as I get back up on my feet again, everybody wants to be my long-lost friend
It's might strange, without a doubt
Nobody wants you when you're down and out
Lord, soon as I get up on my feet again, everybody wants to be my long-lost friend
It's mighty strange, without a doubt
Nobody wants you when you're down and out
That's what I mean, when you're down and out
9/11/10
Bill Sikes
He is one of Dickens's most vicious characters and a very strong force in the novel when it comes to
having control over somebody or harming others. He is portrayed as a rough and barbaric man. He is a
career criminal associated with Fagin, and an eventual murderer. He is very violent and aggressive, prone
to sudden bursts of extreme behaviour. He owns a bull terrier named Bull's Eye, whom he beats until the
dog needs stitches.
Dickens describes his first appearance:
“ The man who growled out these words, was a stoutly-built fellow of about five-and-thirty, in a black
velveteen coat, very soiled drab breeches, lace-up half boots, and grey cotton stockings which enclosed a
bulky pair of legs, with large swelling calves—the kind of legs, which in such costume, always look in an
unfinished and incomplete state without a set of fetters to garnish them. He had a brown hat on his head,
and a dirty belcher handkerchief round his neck: with the long frayed ends of which he smeared the beer
from his face as he spoke. He disclosed, when he had done so, a broad heavy countenance with a beard of
three weeks' growth, and two scowling eyes; one of which displayed various parti-coloured symptoms of
having been recently damaged by a blow.”
His prostitute girlfriend Nancy tolerates his violent and lawless behaviour, perhaps because she, being a
thief since the age of six, needs stability in her life, and because she believes that she loves him.
When Sikes murders Nancy, thinking she has betrayed him, a mob hounds him through the streets of London
until he accidentally hangs himself while trying to escape. The murder is especially gruesome, and is one
of the most graphic, frightening, scenes Dickens ever wrote.
Sikes has almost no redeeming qualities, although Dickens does give him some shading: at the robbery in
the countryside, Sikes, rather than leave Oliver at the scene of his botched burglary of Rose Maylie's
house, picks him up and runs with him as far as he can. This, however, was as much for his own
self-preservation, as he eventually does abandon the seriously wounded boy and shows absolutely no
remorse about doing so. After he brutally beats Nancy to death, he apparently is capable of feeling
guilt—although this is essentially suspicion that Fagin lied to him about her betrayal, and fear of the
possibility of being caught. Sikes lives in Bethnal Green and later moves to the squalid rookery area of
London then called Jacob's Island, east of present-day Shad Thames.
9/10/10
9/7/10
Maytree » Invisible Chains
***NEW*** ENSLAVED AND EXPLOITED: The Story of Sex Trafficking in Canada from Hope for the Sold on Vimeo.